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The best left-handed mouse you can buy in 2021

Best left-handed mouse
(Image credit: SteelSeries)

If you're searching for the best left-handed mouse, you could be in for a bumpy ride. Even in modern, inclusive times, mouse makers are having trouble remembering to cater properly for left-handed computer users – churning out bundles of right-handed mice and not enough for lefties. 

As we're sure you're aware, this can be incredibly frustrating because the humble mouse is one of the most important bits of kit we can own as computer users. And it's especially important for creatives that a mouse is uber-comfortable to use. This is where our guide comes in. 

We've collected the best mice for left-handed users and listed them here, so you can easily find the best one for your needs. Not every mouse is specifically for lefties, many are ambidextrous in design so you can use them comfortably in either hand. You'll notice that some mice on this page come with plenty of additional buttons. These can be configured to help speed up your workflow, and help you be even more productive. Of course, we also have left-handed mice that favour simplicity, and so still with that tried-and-tested two-button design. 

For more ambidextrous options, take a look at our main buying guide to the best mouse around.

Left-handed mouse: the best options available now

Best left-handed mouse: Logitech G903 Left

(Image credit: Logitech)

01. Logitech G903

The best all-round left-handed mouse

Specifications
DPI: 200–12,000
Interface: Lightspeed wireless
Buttons: 11
Features: Powerplay compatible, 5 profiles, mechanical button tensioning
Reasons to buy
+Wireless charging+High accuracy+Lots of buttons
Reasons to avoid
-Expensive

The Logitech G903 is a wireless gaming mouse that does it all. Thanks to 11 programmable buttons and up to 12,000 DPI of accuracy, this left-handed mouse offers more than most could even use. The mechanical button tensioning (which gives you physical feedback through the button clicks) lets you personalise it exactly. Even more useful are the five profiles you can switch between – adjust settings like sensitivity and button uses to enable you to hop between designing, browsing, and gaming uses. Wireless charging using the PowerPlay mat is another great feature that makes that 32-hour battery life even less of a worry. You can leave the lighting on, lowering battery to 24-hours of use, without worry.

Best left-handed mouse: SteelSeries Sensei Ten

(Image credit: SteelSeries)

02. SteelSeries Sensei Ten

The best gaming mouse for left-handed users

Specifications
DPI: 50–18,000 in 50 in increments
Features: TrueMove Pro sensor, 50G acceleration, Tilt Tracking, 60 Million Click Mechanical Switches, Ambidextrous Design
Reasons to buy
+Ambidextrous design+Onboard profile customization
Reasons to avoid
-No braided cable-A bit lightweight

If you're after a left-handed gaming mouse, then your options are limited, but the good news is that many mouse makers are now embracing ambidextrous designs, which means their mice are comfortable to use for both left- and right-handed people. SteelSeries is one of those manufacturers, and the Sensei Ten combines a left-hand-friendly design with a brilliant sensor that makes it fast and accurate to use. There's loads of customisation options, and it comes with a Tilt Tracking feature, which keeps tracking your movements even when you’re lifting your mouse and putting it back down at tilted angles.

Best left-handed mouse: Microsoft Bluetooth Mobile Mouse 3600

(Image credit: Microsoft)

03. Microsoft Bluetooth Mobile Mouse 3600

The best budget mouse for left-handed users

Specifications
DPI: 1000
Interface: Bluetooth
Buttons: 2
Features: No
Reasons to buy
+Really, really cheap+Comfortable
Reasons to avoid
-Smaller than most mice-Basic

The Microsoft Bluetooth Mobile Mouse 3600 is the best left-handed mouse for people on a budget. It's compact and affordable, but crucially, it's well built as well. It's ideal for people who travel a lot and want a dependable wireless mouse that they can easily carry around.

Its ambidextrous design means it's a great choice for left-handed users as well. Microsoft has a formidable reputation when it comes to peripherals, and the Microsoft Bluetooth Mobile Mouse 3600 is a great example of this.

Best left-handed mouse: Mad Catz Rat 1

(Image credit: Mad Catz)

04. Mad Catz Rat 1

Best affordable left-handed mouse

Specifications
DPI: 2,000
Interface: Wired
Buttons: 3
Features: Dynamic ergonomics
Reasons to buy
+Affordable+Customisable build+Attractive design
Reasons to avoid
-Only three buttons

The Mad Catz Rat 1 is a wired mouse that's impressive to look at but somehow remains low in price. The quirky aesthetic is functional too, as the design means the mouse can be adjusted to fit any hand for perfect ergonomic comfort. There are only three buttons, but that keeps this mouse light for travel (it can even be split to make it more compact). With multiple colour options and a very low price, this is a tough mouse to beat.  

Best left-handed mouse: SteelSeries Sensei 310 Left

(Image credit: SteelSeries)

05. SteelSeries Sensei 310

A great high-end left-handed mouse

Specifications
DPI: 100–12,000
Interface: Wired
Buttons: 8
Features: Esports sensor, split-trigger buttons, dual RGb lighting
Reasons to buy
+Esports sensor onboard+Split-trigger buttons+Ambidextrous+32-bit ARM processor
Reasons to avoid
-Not wireless

The SteelSeries Sensei 310 is a mouse built for gamers, meaning it’s crammed full of useful tech that designers and general users alike can benefit from. A whopping 12,000 DPI capability makes this super-sensitive (if you have it set to that high level). An ARM 32-bit processor – once a dream even for smartphones – helps compute all this data so you end up with the smoothest end result, which is what it’s all about really, isn’t it?

Best left-handed mouse: Evoluent VerticalMouse 4

(Image credit: Evoluent)

06. Evoluent VerticalMouse 4

Best vertical mouse for left-handers

Specifications
DPI: 2,600
Interface: Wired
Buttons: 6
Features: Enhanced ergonomics
Reasons to buy
+Pure ergonomic comfort+Highly adjustable
Reasons to avoid
-Expensive

The Evoluent VerticalMouse 4 has gone through many generations since it first appeared in 2002, and it's still going strong. The ergonomic design keeps your wrist from twisting thereby creating maximum comfort and promising long-term wrist health. The optical sensor and pointer are adjustable and buttons are available for fingers and thumbs (there are six in total). This mouse isn't cheap, but as a designer it's worth shelling out a bit more if it means keeping your wrist and hands happy.

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